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1.
Acta Orthop Traumatol Turc ; 54(5): 473-477, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33155554

RESUMO

OBJECTIVE: The aims of this study were, first, to assess the loss of reduction after fixation of Rockwood type V acromioclavicular joint dislocation (ACJD) with the TightRope device (Arthrex, Naples, FL, USA) and, second, to present the functional and radiological outcomes of this treatment. METHODS: We retrospectively reviewed the medical records of 15 patients (12 males; mean age=39.2 years; age range=23-61) with Rockwood type V ACJD who were treated by the TightRope fixation device. The mean follow-up period was 19.3 (range=12-30) months. Functional status was assessed using the Constant-Murley score (CMS) at the final follow-up examination. To determine the reduction loss of ACJ, we measured and compared the coracoclavicular (CC) distance using radiographs with Zanca view in the early postoperative period and at the final follow-up examination. The fixation procedures were performed with an open technique using the TightRope fixation device. RESULTS: The mean CMS at the final follow-up was 93.2 (range=82-100) points. All the patients experienced full recovery of the shoulder's range of motion, were able to return to the activities of daily living, and were satisfied with the treatment. ACJ reduction was successfully achieved in all the patients using the TightRope technique. Postoperative radiographs revealed no reduction loss in the ACJ, and the CC distance was well maintained. The mean CC distance was 19.95 (range=13.1-28.3) mm before surgery. The mean CC distance was 7.47 (range=4.2-11.5) mm in the early postoperative radiographic measurements. This difference was statistically significant (p=0.001). The mean CC distance at the final follow-up examination was 7.70 (range=4.5-11.7) mm. At the final follow-up visit, the shoulders of all the patients were still completely reduced, with a mean difference in the CC of 0.23 (range=0-1.3) mm compared with that in the early postoperative period. The difference in the CC between the early postoperative and final follow-up intervals was not statistically significant (p=0.055). No patient experienced recurrence or required an operation for hardware removal. CONCLUSION: It seems that the TightRope device can provide anatomical restoration in patients with acute type V ACJD without subluxation at the final follow-up examination. LEVEL OF EVIDENCE: Level IV, Therapeutic study.


Assuntos
Fixadores Internos/efeitos adversos , Luxações Articulares , Procedimentos Ortopédicos , Radiografia/métodos , Recuperação de Função Fisiológica , Luxação do Ombro , Articulação Acromioclavicular/diagnóstico por imagem , Articulação Acromioclavicular/lesões , Articulação Acromioclavicular/cirurgia , Atividades Cotidianas , Adulto , Feminino , Humanos , Luxações Articulares/diagnóstico , Luxações Articulares/cirurgia , Masculino , Procedimentos Ortopédicos/efeitos adversos , Procedimentos Ortopédicos/instrumentação , Procedimentos Ortopédicos/métodos , Avaliação de Processos e Resultados em Cuidados de Saúde , Período Pós-Operatório , Amplitude de Movimento Articular , Recidiva , Estudos Retrospectivos , Luxação do Ombro/diagnóstico , Luxação do Ombro/cirurgia , Resultado do Tratamento
2.
Knee Surg Sports Traumatol Arthrosc ; 28(9): 2788-2797, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31119340

RESUMO

PURPOSE: To compare the biomechanical and histological properties of Achilles tendons repaired at different time points during the acute injury period. METHODS: Thirty-six skeletally mature Sprague-Dawley rats underwent bilateral mid-substance Achilles tenotomy. The Achilles tendons were repaired either in the first 24 h (group 1), 24-48 h (group 2), 48-72 h (group 3), or > 72 h (mean: 120 ± 5.2 h) (group 4) after tenotomy. Six weeks after repair, nine tendons per group were assessed biomechanically and histologically. The Stoll histological scoring system was used for histological examination. The groups were compared with each other and native tendons (control group). The correlations between biomechanical and histological results were analysed. RESULTS: There were no significant differences between groups 1, 2 and 3 regarding the mean load to failure; it was significantly lower in group 4. Healed tendons in groups 1, 2 and 3 had significantly greater stiffness than native tendons and group 4 tendons. All healed tendons had a larger cross-sectional area than native tendons. There was no significant difference in tendon length between the groups. There was no significant difference in Young's modulus between the groups; Young's modulus was lower in all the groups than in the control group. Group 1 had significantly higher extracellular matrix organization, cell alignment, cell distribution and nucleus morphology scores and total scores than group 4. Group 1 had significantly higher extracellular matrix organization, cell distribution, vascularization and inflammation scores and total scores than group 3. A significant positive correlation was detected between the maximum load to failure and total histological score. CONCLUSION: Repair of acute Achilles tendon rupture within 48 h, and especially in the first 24 h, provides better biomechanical and histological outcomes. In the clinical practice, the data could be used to decrease re-rupture rates, to achieve more anatomical tendon healing and to implement more effective post-operative rehabilitation programme.


Assuntos
Tendão do Calcâneo/cirurgia , Traumatismos dos Tendões/cirurgia , Cicatrização , Tendão do Calcâneo/lesões , Tendão do Calcâneo/fisiologia , Animais , Fenômenos Biomecânicos , Masculino , Ratos , Ratos Sprague-Dawley , Ruptura/cirurgia , Tenotomia , Fatores de Tempo
4.
SAGE Open Med ; 7: 2050312119837480, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30886717

RESUMO

OBJECTIVE: Nowadays, people tend to spend more time in the closed areas and benefit less from sunlight. In this study, we examined the results of vitamin D measurements of athletes from different disciplines in different months and aimed to determine if the synthesis of vitamin D decreases or not according to exercise environment and month. METHODS: The study was conducted in participants aged 5-52 years. A total of 555 elite-level sportsmen who were admitted to our Sports Medicine Clinic in the study participated in this study. Indoor and outdoor environmental and seasonal effects on the measurements in different months were statistically evaluated. Independent-samples test and definitive statistics were used for statistical analyses and a p-value less than 0.05 has been considered significant. RESULTS: The study group consisted of 229 male and 326 female athletes. The serum 25-hydroxyvitamin D concentration was observed; 120 (21.6%) athletes have severe serum vitamin D deficiency (<11-20 ng/mL). Vitamin D levels were not significantly different from outdoor athletes (393; 70.8%). Winter measurements of vitamin D levels were significantly lower than those measured in autumn (p = 0.000). CONCLUSION: Increasing vitamin D levels are very important especially in participating athletes and additional supplements are recommended whenever necessary. Gender and indoor/outdoor sports participation showed no statistically significant outcomes on vitamin D levels. However, winter season had a negative effect on vitamin D levels. Therefore, adequate precautions should be taken to increase vitamin D, especially during winter, to maintain the best performance of the athletes.

5.
Indian J Orthop ; 53(1): 196-203, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30906002

RESUMO

BACKGROUND: Defects of bone and soft tissue occur frequently after high-energy trauma, infections, and tumor resection. Treatment options are limited and outcomes are controversial in nonunion. Classical reconstruction methods are challenging. We describe a method of internal bone transport for treatment of complicated nonunion of the forearm. This method permits axial and internal bone transport without harming the distorted and complex neurovascular anatomy or soft-tissue envelope. MATERIALS AND METHODS: Five patients (mean age, 27 years) with defect nonunion (3 ulna, 2 radius) were treated. Mean preoperative defect size was 36 mm, mean shortening was 14 (0-30) mm, and the extent of surgical resection was 24 (20-40) mm. Total bone loss due to defect, resection, or shortening was 74 mm. According to Paley classification, two of the patients had B1, and three had B3 defect nonunion. This study treats defect nonunion of the forearm using an internal bone-transport method. Our method involved cannulated screws, a cerclage wire, and a circular fixator being used in combination. When transportation was completed, internal fixation of the docking site with a plate and screws was done, with bone grafting after fixator removal. Bone healing and functional outcomes were assessed with radiographs and disabilities of the arm, shoulder, and hand (DASH) scores, respectively. RESULTS: Mean followup was 67.6 months. Solid osseous union and functional improvement were achieved in all cases. Mean bone loss was 66 mm, mean fixator time was 131.8 days, the lengthening index was 1.3 days/mm, and the fixator index was 2.1 days/mm. DASH score was 82.2 before treatment and 15.36 after treatment. CONCLUSIONS: Using our method, internal bone transport and progressive axial docking of defects can be done with minimal effects on surrounding neurovascular arrangements and soft tissues. Size of fixators can be decreased and formation of painful scar tissue can be avoided.

6.
J Orthop Surg (Hong Kong) ; 27(2): 2309499019837411, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30909790

RESUMO

PURPOSE: Reconstruction of the lateral collateral ligament (LCL) and biceps femoris tendon following proximal fibula resection is controversial. Postoperative knee instability and peroneal nerve dysfunction affect outcome. This study aimed to determine functional, clinical, and radiological outcomes of patients who underwent en bloc proximal fibula resections and to compare clinical and radiological instability rates for primary repair after type I and type II resections. MATERIALS AND METHODS: Eleven patients with primary tumors of the proximal fibula were included. Musculoskeletal Tumor Society (MSTS) score and Lysholm knee score were used in the evaluation of functional outcomes. Clinical outcome was assessed using knee range of motion and knee varus stress test. Radiological outcome was assessed using varus stress knee radiographs. Knee stability was evaluated using the varus stress test at 30° of knee flexion and varus stress knee radiographs and graded in millimeters. RESULTS: Of the 11 tumors, 6 (54.6%) underwent type I resection. In five (45.4%) patients, type II resection was performed. The mean follow-up period was 32 ± 13.9 months (range, 12-55 months; median, 27 months). The mean knee joint lateral opening, MSTS score, and Lysholm knee score with type I versus type II resection were 5.7 ± 1.2 mm versus 6.4 ± 1.1 mm ( p = 0.247), 28.7 ± 1.8 (95.6%) versus 20.4 ± 7.7 (68%) ( p = 0.011), and 92.2 ± 8.8 versus 62.8 ± 20.4 ( p = 0.026), respectively. Postoperative complications of all patients included one (9.1%) deep tissue infection and one (9.1%) long-term knee instability. In one patient (9.1%) who underwent type II resection, above-the-knee amputation was performed after local recurrence. CONCLUSIONS: Primary repair of the LCL and biceps femoris tendon to the surrounding soft tissues after resection of proximal fibular tumors provides good clinical outcomes. Primary repair is a simple technique to perform with minimal morbidity. Peroneal nerve palsy was a problem, especially in type II resections. Level of Evidence: Therapeutic Level III.


Assuntos
Neoplasias Ósseas/cirurgia , Fíbula/cirurgia , Instabilidade Articular/epidemiologia , Osteocondroma/cirurgia , Complicações Pós-Operatórias/epidemiologia , Sarcoma/cirurgia , Adolescente , Adulto , Idoso , Neoplasias Ósseas/diagnóstico por imagem , Feminino , Humanos , Articulação do Joelho , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Osteocondroma/diagnóstico por imagem , Radiografia , Amplitude de Movimento Articular , Estudos Retrospectivos , Sarcoma/diagnóstico por imagem , Adulto Jovem
7.
Acta Orthop Traumatol Turc ; 53(1): 30-34, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29773449

RESUMO

OBJECTIVE: The aim of this study was to discuss the diagnosis and surgical management and their results according to stage of primary bone tumors at ulna and to share our experience on this exceptional location for bone tumors. METHODS: We have retrospectively reviewed our clinics database and identified 23 cases (14 males and 9 females, mean age was 28.9 (range 4-77)) with primary bone tumors and tumor like lesion involvement of ulna. The patients were evaluated according to complaints, type and grade of tumor, treatment, recurrence and functional status. RESULTS: The most common first referral complaint was constrictive pain in 52.1% of the cases, benign tumors and tumor like lesions of the bone constituted 73.9% whereas malignant bone tumors were 26.1%, 39.1% of the lesions were located in distal end of ulna and the mean follow up was 33.8 months (range 8-172 months). Local recurrence has unexpectedly occurred in 3 benign lesions (13.1%). CONCLUSION: Benign bone lesions tend to involve distal and proximal ends, malign bone lesions involve diaphysis mostly. Both benign and malignant diaphyseal lesions of the ulna have better postoperative results regarding the lesions at both ends of ulna. One should also take care of recurrences even after a decade from the primary surgery. LEVEL OF EVIDENCE: Level IV, Therapeutic study.


Assuntos
Neoplasias Ósseas , Procedimentos Ortopédicos , Ulna , Adulto , Neoplasias Ósseas/patologia , Neoplasias Ósseas/cirurgia , Diáfises/patologia , Feminino , Humanos , Masculino , Recidiva Local de Neoplasia/diagnóstico , Estadiamento de Neoplasias , Procedimentos Ortopédicos/efeitos adversos , Procedimentos Ortopédicos/métodos , Complicações Pós-Operatórias/epidemiologia , Estudos Retrospectivos , Turquia/epidemiologia , Ulna/diagnóstico por imagem , Ulna/patologia , Ulna/cirurgia
8.
Knee Surg Sports Traumatol Arthrosc ; 27(3): 898-904, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30269172

RESUMO

PURPOSE: The purpose of this study was to evaluate the role of surgeons' experience with meniscal repairs and meniscectomy decisions, and to determine the factors affecting the disagreement between meniscal repairs and meniscectomy decisions. METHODS: In total, 223 patients with meniscal tears, 106 meniscal repairs, and 117 meniscectomies were included. Six orthopedic surgeons (3: > 5 years; 3: < 5 years' arthroscopy experience) were blinded, and they independently reviewed all preoperative MR images for over a month. Their reviews were compared with arthroscopic interventions performed by a surgeon with > 10 years' arthroscopy experience. Reparability-associated factors were also evaluated using multivariate logistic regression. RESULTS: The first and second evaluation results did not differ significantly between groups (n.s.). There was good agreement between MRI predictions and arthroscopic interventions for both groups (< 5 years' experience: k = 0.248, agreement 62.3%; > 5 years' experience: k = 0.351, agreement 67.3%). Sex, side, and distance of tear from the meniscocapsular junction were not significantly different between agreements and disagreements. Disagreement regarding meniscectomy was significantly higher than those regarding meniscus repair (p = 0.002). Concomitant anterior cruciate ligament (ACL) injury, osteochondral lesions, and medial meniscal tear increased the likelihood of meniscal repair (p = 0.0063, p = 0.0010, and p = 0.0369, respectively). An increased risk of disagreement between MRI and surgical procedure was found in the presence of bucket-handle, horizontal or complex tear, chronic tear, high sports activity and expectation level. CONCLUSION: Surgeon's experience level may influence the prediction of meniscus reparability. Concomitant ACL injury, osteochondral lesions, and presence of medial meniscal tear increase the likelihood of meniscal repair. Tear type, tear chronicity, patient's activity and expectation level may influence the surgeon's operative decision in addition to MRI. LEVEL OF EVIDENCE: III.


Assuntos
Tomada de Decisão Clínica , Imageamento por Ressonância Magnética , Lesões do Menisco Tibial/diagnóstico por imagem , Adolescente , Adulto , Lesões do Ligamento Cruzado Anterior , Artroscopia , Cartilagem Articular/lesões , Competência Clínica , Feminino , Humanos , Masculino , Meniscectomia , Pessoa de Meia-Idade , Lesões do Menisco Tibial/cirurgia , Adulto Jovem
9.
J Orthop Surg (Hong Kong) ; 26(3): 2309499018798180, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30189775

RESUMO

PURPOSE: Primary bone tumors of the fibula are rare. There are only a few studies reporting the incidence, histologic, and anatomic distribution of primary fibula tumors. This study aimed to comprehensively report the incidence, presenting symptoms, and histologic tumor types with the anatomic and histologic distribution of primary bone tumors of the fibula. METHODS: Between January 1983 and December 2017, 6457 primary bone tumors and tumor-like lesions were diagnosed and treated in our musculoskeletal oncology surgery clinic. Of these, 264 (4.08%) were primary bone tumors and tumor-like lesions of the fibula. We retrospectively reviewed patients' records, histopathology records, and radiologic images regarding age, gender, anatomic localization, histopathologic diagnosis, and treatment methods. RESULTS: There were 209 (79.2%) benign and 55 (20.8%) malignant lesions. The most common benign and malignant tumors were osteochondroma (51 of 209; 24.4%) and chondrosarcoma (16 of 55; 29.1%). The proximal fibula was the most common location for both benign and malignant tumors (141 of 209; 67.5% and 45 of 55; 81.8%, respectively), followed by the distal fibula (52 of 209; 24.9% and 8 of 55; 14.5%, respectively) and the diaphysis (17 of 209; 8.14% and 2 of 55; 3.64%, respectively). CONCLUSION: The incidence of primary bone tumors is higher than that reported in previous studies. Benign lesions constitute the majority of cases. One-fifth of all cases are malignant. The most common anatomic site involving the primary fibula tumors is the proximal fibula. LEVEL OF EVIDENCE: III.


Assuntos
Neoplasias Ósseas/epidemiologia , Neoplasias Ósseas/patologia , Fíbula , Adolescente , Adulto , Idoso , Neoplasias Ósseas/cirurgia , Criança , Pré-Escolar , Condrossarcoma/epidemiologia , Condrossarcoma/patologia , Condrossarcoma/cirurgia , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Osteocondroma/epidemiologia , Osteocondroma/patologia , Osteocondroma/cirurgia , Estudos Retrospectivos , Adulto Jovem
10.
Acta Orthop Traumatol Turc ; 52(6): 415-418, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30249436

RESUMO

OBJECTIVE: Chondroblastoma is a benign aggressive tumor which needs surgical treatment and has a recurrence rate up to 35%. Extended (aggressive) curettage is the mainstay of treatment and local adjuvants have been reported to decrease the recurrence rate. METHODS: The recurrence rates and the functional results of 14 patients who were treated in our institution and 2 other patients who were treated elsewhere between the years 2004-2016 were evaluated. Seventeen cases (13 male, 3 female; mean age: 17.1 [range: 13 to 32] years) who had been diagnosed, treated and followed up in our hospital between 2004 and 2016 were evaluated in terms of recurrence rates and functional outcomes. The average follow-up period was 41.6 (range: 12 to 132) months. RESULTS: Five cases of recurrence were observed. Two cases had undergone their primary treatment in another institution. Seven cases were performed curettage alone whereas nine others were administered adjuvant treatments. One of the five recurrence patients was advised to undergo disarticulation. Another was treated with curettage and grafting and the remaining three patients with curettage and cementing. No recurrence was observed in their follow-up period. Their mean MSTS score was 27.3 (range: 4 to 30) over a maximum of 30 points and their functional results were good. CONCLUSION: Chondroblastoma is a tumor with high recurrence rates in the post-treatment period. However, good functional outcomes can be achieved with early diagnosis and appropriate treatment even after recurrence. LEVEL OF EVIDENCE: Level IV, therapeutic study.


Assuntos
Neoplasias Ósseas , Condroblastoma , Curetagem , Recidiva Local de Neoplasia , Adolescente , Adulto , Neoplasias Ósseas/patologia , Neoplasias Ósseas/cirurgia , Condroblastoma/patologia , Condroblastoma/cirurgia , Curetagem/efeitos adversos , Curetagem/métodos , Detecção Precoce de Câncer/métodos , Feminino , Seguimentos , Humanos , Masculino , Recidiva Local de Neoplasia/epidemiologia , Recidiva Local de Neoplasia/terapia , Recuperação de Função Fisiológica , Resultado do Tratamento , Turquia/epidemiologia
11.
Eklem Hastalik Cerrahisi ; 29(2): 117-22, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-30016612

RESUMO

Achilles tendon xanthomas are rarely seen masses that are highly associated with hyperlipidemia. They are manifested in two types: Xanthomas developed secondary to familial hypercholesterolemia and cerebrotendinous xanthomatoses. In this report, we present a case of bilateral Achilles tendon xanthoma secondary to familial hypercholesterolemia and resection along with a portion of the Achilles tendon. The patient was a 49-year-old male who presented to our clinic with complaints of difficulty walking and swelling in both heels. The swellings had started insidiously without a trauma history. The xanthomas were operated at different time points, albeit with the same surgical technique. Quadriceps tendon graft and flexor hallucis longus transfer was used for autografting. Xanthoma should be considered in cases with swellings in the Achilles tendon. Total resection is necessary to avoid recurrence of the xanthomas. Large gaps formed after resection can be filled and reconstruction of the Achilles tendon can be realized using quadriceps tendon autografts (containing bony fragments) and the flexor hallucis longus tendon. We believe a functional ankle and an Achilles tendon can be achieved with the employment of this technique.


Assuntos
Tendão do Calcâneo/cirurgia , Hiperlipoproteinemia Tipo II/complicações , Transferência Tendinosa , Tendões/transplante , Xantomatose/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Xantomatose/etiologia
12.
Acta Ortop Bras ; 26(2): 82-85, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29983622

RESUMO

OBJECTIVE: To assess the histopathologic and biomechanical effects of hyaluronic acid (HA) and high-dose vitamin C (VC) on rat Achilles tendon healing. METHODS: Forty-eight Sprague-Dawley rats were randomized to HA and VC and control groups with equal numbers. Each group was further divided into two subgroups to be sacrificed on Day 15 (n=8) and Day 30 (n=8). The Achilles tendons were cut and repaired. While the control rats remained untreated, HA and VC were administered after repair. The repaired tendons were removed for biomechanical and histopathologic analyses. In the biomechanical tests, the tendons were stretched to failure and maximum forces were measured. For histopathologic examination, the specimens were interpreted semiquantitatively using Movin's grading scale and Bonar scores. RESULTS: The highest mean forces were obtained in the HA group on Day 15 and in the VC group on Day 30, with a significant difference between HA and VC on Day 15 between control and VC on Day 30 (p<0.05). Histological examination showed both Movin and Bonar scores decreased in all groups on Day 30, with significant improvements in the HA and VC groups (p<0.05). CONCLUSION: Our results demonstrated that both VC and HA had therapeutic effects on tendon healing, especially in the late phase. Level of Evidence I; High quality randomized trial with statistically significant difference.


OBJETIVO: Avaliar os efeitos histopatológicos e biomecânicos do ácido hialurônico (AH) e altas doses de vitamina C (VC) na cicatrização do tendão do calcâneo em ratos. MÉTODOS: Quarenta e oito ratos Sprague-Dawley foram randomizados em grupo AH, grupo VC e grupo controle, iguais em número. Cada grupo foi dividido em dois subgrupos a serem sacrificados no Dia 15 (n = 8) e no Dia 30 (n = 8). Os tendões do calcâneo foram cortados e reparados. Enquanto os ratos do grupo controle permaneceram não tratados, os do grupo AH/VC receberam AH e VC após o reparo. Os tendões reparados foram removidos para análises biomecânicas e histopatológicas. Nos testes biomecânicos, os tendões foram estirados até a falha e as forças máximas foram medidas. No exame histopatológico, as amostras foram interpretadas semiquantitativamente usando os escores de Movin e de Bonar. RESULTADOS: As forças médias mais altas foram obtidas no grupo AH no Dia 15 e no grupo VC, no Dia 30, com diferença significativa entre os grupos HA e VC no Dia 15 e entre os grupos controle e VC (p < 0,05). No exame histológico, os escores de Movin e Bonar diminuíram em todos os grupos no dia 30, com melhora significativas nos grupos AH e VC (p < 0,05). CONCLUSÕES: Nossos resultados demonstraram que tanto a VC quanto o AH tiveram efeitos terapêuticos sobre cicatrização do tendão, especialmente na fase tardia. Nível de Evidência I; Estudo clínico randomizado de alta qualidade com ou sem diferença estatisticamente significante.

13.
World J Surg Oncol ; 16(1): 106, 2018 Jun 08.
Artigo em Inglês | MEDLINE | ID: mdl-29884195

RESUMO

BACKGROUND: Some patients experience a non-traumatic pain in the tibial diaphysis similar to that in the clinical and radiological findings of a tumor, an infection or a stress fracture and cannot be definitively diagnosed even after biopsy. In this study, our aim was to exhibit the challenges in the diagnosis of this patient group and to evaluate this type of patients with a limited population in the literature. METHODS: Eighteen extremities of 16 patients, whose complaints of non-traumatic pain in the tibial diaphysis were evaluated by our tumor council and T2-weighted MR scans of the medullary bone had shown hyperintense signal changes or tumor-like appearances, were evaluated with histological, radiological, and clinical results. RESULTS: Lesions were detected in 18 extremities of the 16 patients (seven males, nine females; mean age 23 [range 7 to 51] years). Four of the lesions were in the right tibial diaphysis, ten were in the left, and two were bilateral. Laboratory findings of the patients were normal. Based on the decision of the tumor council, biopsy was performed on 12 patients. All patients' complaints were gone and MRI findings decreased during the follow-up period. The complaints of the three patients who did not have a biopsy decreased after a mean period of three months. CONCLUSIONS: Medullary stress syndrome has been reported in the literature in various forms and in a limited number of cases, including longitudinal stress fracture and transient medullary edema of the bone. In light of our findings, we deduced that biopsy of the diaphyseal lesions in this patient group is essential and that the complaints of this patient group declined in the earlier term in comparison to the patients who were not performed biopsy.


Assuntos
Doenças Ósseas/diagnóstico , Doenças da Medula Óssea/diagnóstico por imagem , Diáfises/diagnóstico por imagem , Edema/diagnóstico por imagem , Tíbia/diagnóstico por imagem , Adolescente , Adulto , Biópsia , Doenças Ósseas/patologia , Doenças da Medula Óssea/patologia , Criança , Diáfises/patologia , Edema/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Dor Musculoesquelética/etiologia , Prognóstico , Tíbia/patologia , Adulto Jovem
14.
J Orthop Surg (Hong Kong) ; 26(2): 2309499018777885, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29848169

RESUMO

PURPOSE: To investigate the biomechanical, histological, and radiological effects of sildenafil and pentoxifylline on femoral fracture healing in rats. METHODS: Forty-eight Sprague-Dawley rats were divided into three groups equally according to the pharmacological agents to be investigated. Femoral shaft fractures were formed in the left side. Group 1 (control group), group 2, and group 3 were administered with saline, sildenafil, and pentoxifylline during the fracture healing process, respectively. Eight rats from each group were euthanized on days 15 and 30. X-ray images of the rats were taken after euthanasia for radiographical examination. Femur samples were subjected to histopathological and biomechanical (three-point bending) examinations. RESULTS: Radiologically, no difference between the Goldberg scores of the groups was found for day 15 ( p > 0.05), while higher Goldberg scores were obtained from group 2 than that of group 1 ( p > 0.05) and group 3 ( p < 0.05) for day 30. In the biomechanical analysis, higher mean breaking forces were found both for day 15 and day 30 from group 2 than those obtained from group 1 (for day 15 p > 0.05 and day 30 p > 0.05) and group 3 (for day 15 p < 0.05 and day 30 p < 0.01). Higher mean absorbed energy values were obtained from group 2 than those obtained from group 1 (for day 15 p > 0.05 and day 30 p < 0.05) and group 3 (for day 15 p < 0.01 and day 30 p < 0.01). A significant difference was not found between the histological scores of all groups ( p > 0.05) for day 15, while the histological score of group 1 on day 30 was found to be significantly lower than that of sildenafil and pentoxifylline groups ( p < 0.05). CONCLUSION: Sildenafil had a positive effect on fracture healing, while pentoxifylline did not provide consistent positive effect.


Assuntos
Fraturas do Fêmur/terapia , Consolidação da Fratura/efeitos dos fármacos , Inibidores de Fosfodiesterase/uso terapêutico , Animais , Fenômenos Biomecânicos , Fraturas do Fêmur/diagnóstico por imagem , Fraturas do Fêmur/patologia , Masculino , Radiografia , Ratos , Ratos Sprague-Dawley
15.
Acta ortop. bras ; 26(2): 82-85, Mar.-Apr. 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-949721

RESUMO

ABSTRACT Objective: To assess the histopathologic and biomechanical effects of hyaluronic acid (HA) and high-dose vitamin C (VC) on rat Achilles tendon healing. Methods: Forty-eight Sprague-Dawley rats were randomized to HA and VC and control groups with equal numbers. Each group was further divided into two subgroups to be sacrificed on Day 15 (n=8) and Day 30 (n=8). The Achilles tendons were cut and repaired. While the control rats remained untreated, HA and VC were administered after repair. The repaired tendons were removed for biomechanical and histopathologic analyses. In the biomechanical tests, the tendons were stretched to failure and maximum forces were measured. For histopathologic examination, the specimens were interpreted semiquantitatively using Movin's grading scale and Bonar scores. Results: The highest mean forces were obtained in the HA group on Day 15 and in the VC group on Day 30, with a significant difference between HA and VC on Day 15 between control and VC on Day 30 (p<0.05). Histological examination showed both Movin and Bonar scores decreased in all groups on Day 30, with significant improvements in the HA and VC groups (p<0.05). Conclusion: Our results demonstrated that both VC and HA had therapeutic effects on tendon healing, especially in the late phase. Level of Evidence I; High quality randomized trial with statistically significant difference.


RESUMO Objetivo: Avaliar os efeitos histopatológicos e biomecânicos do ácido hialurônico (AH) e altas doses de vitamina C (VC) na cicatrização do tendão do calcâneo em ratos. Métodos: Quarenta e oito ratos Sprague-Dawley foram randomizados em grupo AH, grupo VC e grupo controle, iguais em número. Cada grupo foi dividido em dois subgrupos a serem sacrificados no Dia 15 (n = 8) e no Dia 30 (n = 8). Os tendões do calcâneo foram cortados e reparados. Enquanto os ratos do grupo controle permaneceram não tratados, os do grupo AH/VC receberam AH e VC após o reparo. Os tendões reparados foram removidos para análises biomecânicas e histopatológicas. Nos testes biomecânicos, os tendões foram estirados até a falha e as forças máximas foram medidas. No exame histopatológico, as amostras foram interpretadas semiquantitativamente usando os escores de Movin e de Bonar. Resultados: As forças médias mais altas foram obtidas no grupo AH no Dia 15 e no grupo VC, no Dia 30, com diferença significativa entre os grupos HA e VC no Dia 15 e entre os grupos controle e VC (p < 0,05). No exame histológico, os escores de Movin e Bonar diminuíram em todos os grupos no dia 30, com melhora significativas nos grupos AH e VC (p < 0,05). Conclusões: Nossos resultados demonstraram que tanto a VC quanto o AH tiveram efeitos terapêuticos sobre cicatrização do tendão, especialmente na fase tardia. Nível de Evidência I; Estudo clínico randomizado de alta qualidade com ou sem diferença estatisticamente significante.

16.
Chin J Traumatol ; 21(2): 104-108, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29598844

RESUMO

PURPOSE: Tibia plateau fracture (TPF) treatment aims at achieving a stable, aligned, mobile, painless knee and preventing post-traumatic osteoarthritis. To achieve this goal, surgeons consider criteria such as patients' characteristics, severity, risk of complications, fracture displacement/depression, degree of soft tissue injury. However, body mass index (BMI) is not considered as a risk factor in literature. Our study was conducted to find out any possible correlation between BMI and functional scores or radiological score separately. METHODS: Retrospective analysis of case series between 2011 and 2014 was done on the database of a tertiary hospital in Istanbul. There were 67 TPF patients (54 males, 13 females) in the study. Relationship between BMI and functional knee scores or radiological score was compared statistically. Closed fractures with both high-energy and low-energy injury were included in the study. Patients with open fracture, multi-trauma presence, meniscus and/or ligamentous injury, increased co-morbidity, inadequate records (25 cases in all) were excluded. Surgery type, Schatzker classification, injury side, trauma energy, and gender were considered as possible risk factors. Binary regression analysis was done for possible factors affecting functional knee scores and radiologic score. RESULTS: Model summary calculations were done as Nagelkerke R2 test for Knee Society score, Lysholm knee score, and Ahlback and Rydberg radiologic scores, which were 0.648, 0.831, and 0.327 respectively. Homer-Lemeshow test values were 0.976, 0.998, and 0.362, respectively. There is negative correlation between BMI and both knee function scores. There is no correlation between BMI and radiologic score. CONCLUSION: An increase in BMI has a negative effect on functional knee scores after surgical treatment of TPFs. Therefore, BMI should be considered as a risk factor for surgical treatment of TPFs.


Assuntos
Índice de Massa Corporal , Fraturas da Tíbia/cirurgia , Adulto , Idoso , Feminino , Humanos , Articulação do Joelho/fisiopatologia , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fraturas da Tíbia/fisiopatologia
17.
Acta Orthop Traumatol Turc ; 51(6): 492-494, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29056390

RESUMO

This article presents a 48-year-old male patient who presented with pain in the left forearm and weakness and clumsiness in the left hand of 6 months' duration. Flexor motor strength loss of the thumb and the index finger was present and neurophysiologic tests showed findings compatible with axonal injury in the anterior interosseous nerve (AIN) innervated muscles. Magnetic resonance imaging revealed a space-occupying lesion in the proximal forearm resembling a glomus tumor. Excision of the mass and release of the AIN were performed. Histopathology confirmed a glomus tumor, and the patient remains asymptomatic at 1 year postoperatively. We stress the importance of imaging studies in patients when a suspected secondary nature of nerve entrapment is present.


Assuntos
Descompressão Cirúrgica/métodos , Antebraço , Tumor Glômico , Síndromes de Compressão Nervosa , Dissecação/métodos , Dedos/inervação , Antebraço/diagnóstico por imagem , Antebraço/patologia , Tumor Glômico/complicações , Tumor Glômico/patologia , Tumor Glômico/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Síndromes de Compressão Nervosa/diagnóstico , Síndromes de Compressão Nervosa/etiologia , Síndromes de Compressão Nervosa/fisiopatologia , Síndromes de Compressão Nervosa/cirurgia , Exame Neurológico/métodos , Polegar/fisiopatologia , Resultado do Tratamento
18.
J Foot Ankle Surg ; 56(6): 1180-1187, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29079234

RESUMO

Primary bone tumors of the foot are rare lesions. The purpose of the present study was to evaluate the clinical manifestations, treatment modalities, and recurrences of various primary bone tumors of the foot from a specialized center for orthopedic oncology. Among 3681 musculoskeletal tumor cases, which were diagnosed and surgically treated in our hospital from 1983 to 2013, 166 primary tumor and tumor-like bone lesions of the foot (4.5%) were retrospectively reviewed regarding age, gender, localization, biopsy-revealed diagnosis, applied treatment modalities, follow-up period, and recurrence, if any. Of the 166 primary bone tumors of the foot, 155 (93.4%) were benign and 11 (6.6%) were malignant. The most common primary benign bone tumor was a unicameral bone cyst (57 of 155; 36.8%), and the most common malignant tumor was chondrosarcoma (7 of 11; 63.6%). The hindfoot was the most common location for both primary benign (104 of 155; 67.1%) and malignant (6 of 11; 54.5%) bone tumors of the foot. The results of our study have confirmed that the radiologic findings can be confusing owing to the structural and histopathologic features of the bones of the foot; thus, histopathologic diagnosis should be considered for foot involvement. Because the characteristics of the compartments in the foot allow for the rapid spread of malignant lesions, aggressive surgical management and wider resection are recommended to prevent recurrence and further spread.


Assuntos
Neoplasias Ósseas/epidemiologia , Doenças do Pé/epidemiologia , Recidiva Local de Neoplasia/epidemiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Neoplasias Ósseas/diagnóstico por imagem , Neoplasias Ósseas/terapia , Criança , Pré-Escolar , Feminino , Ossos do Pé/diagnóstico por imagem , Ossos do Pé/cirurgia , Doenças do Pé/diagnóstico por imagem , Doenças do Pé/terapia , Humanos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/prevenção & controle , Radiografia , Cintilografia , Adulto Jovem
19.
Acta Orthop Traumatol Turc ; 51(6): 455-458, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29032901

RESUMO

OBJECTIVE: The aim of this study was to compare the long-term clinical and radiological results of Acromioclavicular (AC) fixation with K-wires (the modified Phemister procedure) and Coracoclavicular (CC) fixation with the Bosworth screw in the surgical treatment of Type 3 AC joint dislocations. METHODS: Thirty-two patients with complete set of medical records and who received surgical treatment between September 2005 and January 2009 due to acute Rockwood Type 3 AC joint dislocation and properly attended their follow-ups were retrospectively evaluated. Sixteen patients (13 males, 3 females; mean age: 38, range: 24-52 years) were treated with CC fixation with Bosworth screw (Group 1), and the other 16 (12 males, 4 females; mean age: 53.3, range: 38-64 years) with AC fixation using K-wires (Group 2). RESULTS: The mean follow-up time was 96 months for Group 1 and 93 months for Group 2 patients (p > 0.05). The mean Constant-Murley score at the final follow-up was 84.7 in Group 1 and 87.3 in Group 2 (p = 0.069). Radiological evaluation of the patients revealed AC arthrosis in 2 and 3 patients in Group 1 and 2, respectively. In Group 2, one patient had a recurrent dislocation, three patients had AC arthrosis and two patients had ossification in the CC ligament (Fig. 2). There was no superficial or deep wound infection in Group 1, while two patients from Group 2 had a superficial wound infection. CONCLUSIONS: Our results suggest that both techniques are reliable and provide adequate reduction and similar outcomes in terms of functionality and pain levels, following the reduction of Type 3 AC joint dislocations. With lower rates of wound site infection in the early and AC arthrosis in the late postoperative period, CC fixation method with the Bosworth screw may be a better surgical option than AC fixation method with K-wires. LEVEL OF EVIDENCE: Level III, Therapeutic study.


Assuntos
Articulação Acromioclavicular , Fixadores Externos , Fixadores Internos , Luxações Articulares , Efeitos Adversos de Longa Duração , Procedimentos Ortopédicos , Dor Pós-Operatória , Articulação Acromioclavicular/fisiopatologia , Articulação Acromioclavicular/cirurgia , Adulto , Feminino , Humanos , Luxações Articulares/diagnóstico , Luxações Articulares/fisiopatologia , Luxações Articulares/cirurgia , Ligamentos Articulares/cirurgia , Efeitos Adversos de Longa Duração/diagnóstico , Efeitos Adversos de Longa Duração/etiologia , Efeitos Adversos de Longa Duração/fisiopatologia , Masculino , Pessoa de Meia-Idade , Procedimentos Ortopédicos/efeitos adversos , Procedimentos Ortopédicos/instrumentação , Procedimentos Ortopédicos/métodos , Dor Pós-Operatória/diagnóstico , Dor Pós-Operatória/etiologia , Radiografia/métodos , Recuperação de Função Fisiológica , Estudos Retrospectivos , Resultado do Tratamento
20.
Acta Orthop Traumatol Turc ; 51(3): 191-196, 2017 May.
Artigo em Inglês | MEDLINE | ID: mdl-28330700

RESUMO

PURPOSE: This study investigated the short-term effects of KT on back pain (BP) in patients with Lenke Type 1 adolescent idiopathic scoliosis (AIS). METHODS: We chosen Lenke Type 1 scoliosis who have had only back pain (the localization of the pain: the only in the apical convex edge). Forty patients suffering from BP with Lenke Type 1 AIS were randomly separated into two groups, Group 1 (20 patients) and Group 2 (20 patients). Group 1 was given KT with tension and home exercises and Group 2 was given KT without tension and home exercises. KT and home exercises was applied to the thoracic area of the patients in both groups for four weeks. Pain intensity was measured using a visual analog scale (VAS) and SRS-22 (subtotal SRS-20) before and after treatment. RESULTS: Mean age of both groups was 16.1 years. Mean Cobb angle of the thoracic scoliosis was 31.8° (range: 17°-44°) in Group 1 and 32.8° (range: 19°-43°) in Group 2 before the treatment. The decrease in VAS score of Group 1 after taping was higher than that of Group 2. The difference between the pre- and post-treatment VAS scores of both groups was statistically significant (p < 0.05). The increase in mean SRS-20 score of Group 1 following taping application was significantly higher than the increase in the control group (p < 0.05). CONCLUSION: Results demonstrated that KT application with tension effectively leads to back pain relief shortly after application. In addition, KT has a positive impact on quality of life. Thus, KT may be a suitable intervention in treating back pain of patients with AIS. LEVEL OF EVIDENCE: Level 1, Therapeutic study.


Assuntos
Fita Atlética , Dor nas Costas/terapia , Terapia por Exercício/métodos , Escoliose/complicações , Adolescente , Dor nas Costas/diagnóstico , Dor nas Costas/etiologia , Feminino , Seguimentos , Humanos , Masculino , Medição da Dor , Estudos Prospectivos , Qualidade de Vida , Escoliose/terapia , Fatores de Tempo , Escala Visual Analógica
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